Table 2.

Thyroid Hormone and Thyrotropin Levels in Great Apes

	NoncongenitalHypothyroidism				Euthyroid great apes
	T4 μg/dL	F-T4 ng/dL	T-T3 ng/dL	TSH mIU/L	n	T4 μg/dL	F-T4 ng/dL	T-T3 ng/dL	TSH mIU/L	References
Gorillas
1F	<1.1a	<0.04		85.4	3	8.2, 5.1, 5.9	1.4, 1.5, 1.9		6.7, 10.8, 8.9	(31)
	8.7b	1.8		4
Kit (hu)					5	(5.1–12.6)				(32)
Range						5.1–8.1			6.7–10.8	(40)
Kit (hu)						(4.5–12.5)
Chimpanzees
1F	0.2	0.05		3.8	1	7.5	2.75		3.0	(33)
Kit (hu)						(5–12)	(1.1–4.1)		(1.9–5.4)
Adult M					5	4.8±0.8		109±27		(39)
Range						(3.7–5.9)		(87–155)
Adult F					17	5.8c		148c		(49)
Adult M					9	9.0c		70c
Orangutans				ng/mL					ng/mL
1F	3.3a		139	3.28						(34)
	10.8b		274	norm
Kit						(4.5–12.0)		(230–420)	(0.35–5.50)
					4	2.0–4.7			0.4–8.6	(40)
Kit						(5.0–12.6)			(0.4–5.0)

Parentheses indicate the range of values.

^aBefore treatment.

^bAfter T4 treatment.

^cMean estimated from Ref. (49).

TSH, thyrotropin; T3, triiodothyronine; Kit (hu), range for humans in assay kit.

Sources: Refs. (31–34,39,40).