Table 3. Peaks of Activation for the Semantic Condition Compared to Resting Baseline in the HC and COS Groups.

Semantic Condition vs. Resting Baseline			Healthy Control Children				Children with Schizophrenia
Anatomical Regions	BA		x	y	z	t	x	y	z	t
Inferior Frontal Gyrus	44	L	-54	18	16	15.02	-58	12	28	6.66
	45	L	-56	24	6	10.73
	46	L	-52	30	12	5.13	-50	24	24	5.37
	47	L	-42	26	2	6.48
	45	R	48	20	4	10.04
	46	R	36	32	12	5.12
	47	R	38	40	-8	8.35	28	24	-4	6.59
Dorsal Lateral Prefrontal Cortex	9	L	-40	0	42	6.31
	9	R	34	14	40	5.16
	46	R	40	38	20	9.29
Presupplementary Motor Area	6	L	-4	14	54	8.06
Premotor Cortex	6	L					-52	10	8	5.30
Dorsal Medial Prefrontal Cortex	8	L	-14	24	40	7.48	-8	30	48	7.83
	9	L	-10	50	34	5.68	-4	40	32	7.55
	8	R	2	22	44	10.88
	9	R	6	42	30	6.90	2	54	30	3.99
Anterior Cingulate Cortex	32	R	4	36	28	7.17
Superior Temporal Gyrus	22	L	-56	-22	4	16.51	-56	-24	0	5.07
	42	L	-48	-30	8	10.49	-60	-20	6	7.62
	22	R	52	-32	6	13.91	56	-14	2	7.08
	42	R	42	-26	10	6.86	50	-30	8	5.11
Middle Temporal Gyrus	21	L	-54	-46	4	7.86	-56	-14	-4	6.86
	21	R	48	-42	0	5.22	56	-34	-2	7.05
Inferior Parietal Lobule	40	L	-44	-34	52	5.79	-50	-34	48	5.59
Occipital Gyrus	18	L	-32	-84	0	7.32
Lingual Gyrus	18	R	14	-90	2	6.12
Insula		L	-34	22	2	6.17
Caudate Nucleus		L	-14	16	10	5.82
		R	12	6	16	7.21
Putamen		L	-26	2	10	8.66
Thalamus		L	-12	-10	8	6.69
		R	6	-8	10	5.57
Cerebellum		L	-12	-76	-16	6.59
		R	24	-78	-26	10.46	12	-50	-18	5.90

HC refers to health control subjects; COS refers to subjects with childhood-onset schizophrenia; BA refers to putative Brodmann Area; L and R refer to left and right hemispheres; x, y, and z refer to the Talairach coordinates corresponding to the left-right, anterior-posterior, and inferior-superior axes, respectively; t refers to the highest t score within a region.