Table 4. Peaks of Activation for the Syntactic Condition Compared to Resting Baseline in the HC and COS Groups.
| Syntactic Condition vs. Resting Baseline | Healthy Control Children | Children with Schizophrenia | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Anatomical Regions | BA | x | y | z | t | x | y | z | t | |
| Inferior Frontal Gyrus | 44 | L | -58 | 16 | 16 | 8.88 | ||||
| 45 | L | -56 | 22 | 8 | 9.60 | |||||
| 47 | L | -52 | 30 | -8 | 6.02 | |||||
| 44 | R | 44 | 14 | 14 | 5.89 | 46 | 14 | 26 | 5.93 | |
| 45 | R | 52 | 18 | 18 | 6.63 | 36 | 20 | 20 | 6.08 | |
| 47 | R | 40 | 20 | -2 | 6.12 | |||||
| Dorsal Lateral Prefrontal Cortex | 6 | L | -38 | 0 | 46 | 6.30 | ||||
| 9 | L | -38 | 2 | 42 | 6.99 | |||||
| 9 | R | 38 | 14 | 42 | 6.70 | |||||
| 46 | R | 40 | 36 | 24 | 5.96 | |||||
| Presupplementary Motor Area | 6 | L | -2 | 14 | 56 | 10.06 | ||||
| 6 | R | 4 | 10 | 56 | 6.02 | |||||
| Dorsal Medial Prefrontal Cortex | 8 | L | -2 | 22 | 46 | 8.81 | ||||
| 9 | L | -10 | 36 | 32 | 6.46 | |||||
| 8 | R | 2 | 26 | 48 | 10.41 | |||||
| 9 | R | 6 | 36 | 32 | 6.96 | |||||
| Anterior Cingulate Cortex | 32 | R | 2 | 20 | 42 | 10.82 | ||||
| Precentral Gyrus | 4 | L | -32 | -6 | 54 | 5.06 | ||||
| Superior Temporal Gyrus | 22 | L | -64 | -14 | 2 | 8.83 | -52 | -24 | 2 | 6.55 |
| 42 | L | -56 | -18 | 6 | 11.27 | -46 | -30 | 12 | 7.51 | |
| 22 | R | 50 | -10 | 0 | 11.90 | 58 | -28 | 4 | 10.16 | |
| Middle Temporal Gyrus | 21 | L | -56 | -48 | 8 | 5.91 | -64 | -16 | 0 | 5.96 |
| 21 | R | 56 | -18 | -4 | 5.63 | 54 | 0 | -8 | 6.06 | |
| Inferior Parietal Lobule | 40 | L | -42 | -34 | 52 | 5.91 | ||||
| Insula | R | 34 | 16 | 2 | 7.03 | |||||
| Caudate Nucleus | R | 12 | 4 | 18 | 5.41 | |||||
| Putamen | L | -16 | 4 | 8 | 9.94 | |||||
| Thalamus | L | -14 | -14 | 14 | 5.85 | |||||
| R | 8 | -2 | 8 | 5.83 | ||||||
| Cerebellum | L | -16 | -80 | -22 | 5.71 | |||||
| R | 28 | -70 | -24 | 7.49 | ||||||
HC refers to health control subjects; COS refers to subjects with childhood-onset schizophrenia; BA refers to putative Brodmann Area; L and R refer to left and right hemispheres; x, y, and z refer to the Talairach coordinates corresponding to the left-right, anterior-posterior, and inferior-superior axes, respectively; t refers to the highest t score within a region.