Table 3.
Effect of depression on time to first cardiac hospitalization
| Analysis Model Parameter |
Hazard Ratio (95% CI) |
P-value |
|---|---|---|
| 1Unadjusted | ||
| Major vs. No Depression | 2.69 (1.95, 3.70) |
<.001 |
| Minor vs. No Depression | 1.99 (1.44, 2.76) |
<.001 |
| Major vs. Minor Depression | 1.35 (0.96, 1.88) |
.08 |
| 2Adjusted | ||
| Major vs. No Depression | 2.54 (1.84, 3.53) |
<.001 |
| Minor vs. No Depression | 2.22 (1.59, 3.08) |
<.001 |
| Major vs. Minor Depression | 1.15 (.81, 1.62) |
.43 |
| ENRICHD All-Cause Mortality Risk Score | 1.27 (1.11, 1.45) |
<.001 |
Kaplan-Meier curves are provided in Figure 1.
The effect of depression is controlled for the imputed, ENRICHD all-cause mortality risk score and a random frailty term for study site.