TABLE 1.
Placebo | CEE | CEE+MPA | % Change CEE vs Placebo | % Change CEE+MPA vs Placebo | % Change CEE+MPA vs CEE | |
---|---|---|---|---|---|---|
TC, mmol/L | 6.20±0.93 | 5.53±0.67 | 5.27±0.67 | −9±17 | −13±16 | −5±6 |
TG, mmol/L | 1.64±0.81 | 1.78±1.00 | 1.58±0.54 | +16±41 | +12±50 | +2±46 |
LDL-C, mmol/L | 3.54±0.93 | 2.95±0.78 | 2.87±0.80 | −14±20 | −17±21 | −2±9 |
HDL-C, mmol/L | 1.50±0.52 | 1.66±0.49* | 1.55±0.52‡ | +13±11 | +6±13 | −6±6 |
HDL2-C, mmol/L | 0.52±0.39 | 0.66±0.34† | 0.54±0.36 | +37±43 | +21±44 | −13±16 |
HDL3-C, mmol/L | 0.96±0.21 | 1.00±0.16 | 1.00±1.26 | +7±17 | +6±23 | −1±13 |
ApoA-I, g/L | 1.40±0.24 | 1.61±0.23* | 1.50±0.25†‡ | +19±16 | +10±14 | −7±6 |
LpAI, g/L | 0.53±0.15 | 0.65±0.20* | 0.55±0.17‡ | +26±19 | +6±15 | −18±16 |
LpAI:AII, g/L | 0.88±0.11 | 0.96±0.10 | 0.95±0.10† | +10±12 | +9±8 | 0±11 |
Data are presented as mean±SD
Significantly different from placebo:
P<0.02,
P<0.05.
Significantly different from CEE:
P<0.05.