Table 1.

FMRI activation peaks for the main effects of verbal fluency.

Subjects	Z-score	Cluster size	Df, corrected p-value (FWE)	Coordinates (x, y, z) in MNI space	Anatomical locations of maxima
Controls	Infinity	12,258	85, p < 0.0001	−44, 22, 24	Left middle frontal gyrus
	Infinity	12,258	p < 0.0001	−30, 24, 0	Left inferior frontal gyrus
	6.37	499	p < 0.0001	32, 22, 0	Right inferior frontal gyrus
	3.88	75	–	−28, −20, −10	Left hippocampus
Left TLE	Infinity	13,124	85, p < 0.0001	−50, 8, 20	Left middle frontal gyrus
	Infinity	13,124	p < 0.0001	−32, 22, 0	Left inferior frontal gyrus
	6.45	593	p < 0.0001	32, 24, 0	Right inferior frontal gyrus
	5.20	59	–	−30, −24, −8	Left hippocampus
Right TLE	Infinity	8320	85, p < 0.0001	−50, 10, 22	Left middle frontal gyrus
	7.28	8320	p < 0.0001	−32, 22, 0	Left inferior frontal gyrus
	5.8	772	p < 0.0001	32, 22, 2	Right inferior frontal gyrus
	2.43	22	–	−30, −26, −6	Left hippocampus
Group comparisons between patients and controls for the main effects of verbal fluency
Left TLE < controls	4.19	47	85, p < 0.0001 (uncorrected)	−44, 26, 26	Left middle frontal gyrus
Right TLE < controls	4.48	127	85, p < 0.0001 (uncorrected)	−44, 24, 26	Left middle frontal gyrus
Left TLE versus right TLE	ns	–	ns	–	–

MNI space, coordinates related to a standard brain defined by the Montreal Neurological Institute (MNI); ns, not significant; TLE, temporal lobe epilepsy.