Table 2.
Ambient temperature | Baseline HLI | Maximal decrease from baseline after microinfusion |
|
---|---|---|---|
Vehicle | Senktide | ||
21.5 C | 0.35 ± 0.03 | 0.11 ± 0.02a | 0.11 ± 0.05a |
29.0 C | 0.42 ± 0.03 | 0.15 ± 0.05a | 0.06 ± 0.02 |
Baseline values represent the average heat loss index (HLI) ± sem during the hour before infusion in OVX + E2 rats (n = 11 at each ambient temperature). Vehicle and senktide values represent the maximal decrease from baseline during the first 30 min after microinfusion (n = 5–6 microinfusions/group).
Significantly different from baseline.