Table 1.
Males |
Females |
|||
---|---|---|---|---|
cort+/+ (mean ± sem) | cort−/− (mean ± sem) | cort+/+ (mean ± sem) | cort−/− (mean ± sem) | |
Somatotrophs | 55.92 ± 2.01 | 56.70 ± 2.10 | 44.70 ± 1.82 | 44.57 ± 1.16 |
Lactotrophs | 18.62 ± 0.92 | 20.76 ± 1.29 | 21.35 ± 2.33 | 23.01 ± 1.19 |
Corticotrophs | 11.41 ± 1.34 | 14.11 ± 2.24 | 9.85 ± 1.16 | 11.86 ± 1.40 |
Thyrotrophs | 6.78 ± 0.65 | 6.64 ± 0.57 | 5.71 ± 0.46 | 5.76 ± 0.80 |
Gonadotrophs | 8.10 ± 0.76 | 8.69 ± 0.94 | 6.72 ± 0.51 | 5.69 ± 0.22 |
Values represent the mean ± sem (three to four pictures/immunohistochemistry per genotype/mice), where the proportions shown were derived from counting more than 1000 cells/slide for each pituitary hormone tested.