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. 2011 Nov 29;2:89. doi: 10.3389/fphys.2011.00089

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Copyright © 2011 Valluru, Staton, Reed and Brown.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits use, distribution, and reproduction in other forums, provided the original authors and source are credited.

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Schematic representation of Endoglin expression in different cell types during the wound healing process. Endoglin is expressed on stem cells and proliferating cells, and is an expression marker for MSCs, HSCs, and megakaryocyte–erythroid progenitors. Eng+9 and Eng+7 function as potent hematoendothelial enhancers and Endoglin is expressed in proliferating endothelial cells, VSMCs, pericytes, and basal keratinocytes. The functional role of endoglin on all these cell types in wound healing is not currently well understood.