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Re-synchronization of body temperature (i), energy expenditure (ii), and physical activity (iii) diurnal variations in wild-type versus CCM mice following a reversal of the light/dark cycle (LDR; panel A). Changes in body weight between young/aged, wild-type/CCM, and control/SSM mice during the 16 week protocol (panel B). Values are expressed as mean ± SEM (n=3–16).
