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Correlation between the BCIC and BM-MSC. BM samples from primary breast cancer patients were interrogated for ALDH function using the aldefluor® assay (Stem Cell Technologies, Vancouver, BC). Within the aldefluor+ BM-MNC subset, BCIC phenotype was defined as CD326+CD45−CD44+CD24low and its percentage is correlated with BM-MSC that co-expressed GD2 and CD271 (either CD45−GD2+CD200+CD271+ or CD45−GD2+CD271+).
