Table 1.
Characteristics of practice guidelines: reporting of conflicts of interest.
| Conflicts of interest | Conflicts of interest | Exact | ||
| reported | not reported | p-value | ||
| N = 7 | N = 184 | |||
| Journal | NEJM | 0 | 7 | 0.026 |
| JAMA | 4 | 31 | ||
| Lancet | 0 | 9 | ||
| Annals | 2 | 31 | ||
| BMJ | 1 | 17 | ||
| Pediatrics | 0 | 89 | ||
| Year | 1979 | 0 | 22 | <0.001 |
| 1984 | 0 | 40 | ||
| 1989 | 0 | 47 | ||
| 1994 | 0 | 42 | ||
| 1999 | 7 | 33 | ||
| Disclosure policy | Yes | 7 | 108 | 0.043 |
| No | 0 | 76 | ||
| Focus | Therapy | 1 | 59 | 0.14 |
| Prevention | 3 | 100 | ||
| Both | 3 | 25 | ||
| Main country | Europe | 1 | 25 | 1.00 |
| America | 6 | 159 | ||
| Group Authorship | Yes | 6 | 155 | 1.00 |
| No | 1 | 29 | ||
| Drug Intervention* | Yes | 2 | 50 | 1.00 |
| No | 5 | 134 | ||
| Funding | Government | 1 | 39 | <0.001 |
| Private | 2 | 9 | ||
| University | 0 | 35 | ||
| Other† | 1 | 98 | ||
| Mixed† | 3 | 3 | ||
| Authors ‡ | 1-2 | 1 | 30 | 0.004 |
| 3-9 | 2 | 22 | ||
| 10-17 | 3 | 2 |
P-values are based on Fisher's exact test. * emphasis placed on medications rather than on vaccines, devices, surgical interventions, nutritional interventions, counseling, screening, rehabilitation and other non-pharmaceutical interventions † other sources of funding include mostly professional organizations (American College of Physicians, American Academy of Pediatrics, American Medical Association); mixed source of funding is defined as a combination of two or more of the four categories of funding ‡ n=60 for this analysis; 30 guidelines did not have group authorship and another 30 guidelines specified specific individuals who were primarily responsible for writing the manuscript, even if group authorship was mentioned