Table 3.
Overlapping genes in PC-3 and DU145 docetaxel resistant cells
| Gene | Function | 8B2 | 8B2 DOX | 1-INT | 1-INT DOX | DU145 T2 |
| BCL6: B-cell CLL/lymphoma 6 | Regulation of cell death/apoptosis | 3.42 | 4.66 | 3.37 | 5.26 | −2.13 |
| CXCL5: chemokine (C-X-C motif) ligand 5 | Regulation of cell growth/proliferation | −3.49 | −4.30 | −2.59 | −2.87 | 7.53 |
| LAMC2: laminin, gamma2 | Extracellular matrix | −5.72 | −6.02 | −2.55 | −2.63 | 1.92 |
| HSPB8: heat shock 22 kDa protein 8 | Response to stress/chemical stimulus | −3.66 | −3.65 | −2.41 | −2.77 | 3.01 |
| F3: coagulation factor III (thromboplastin, tissue factor) | Response to stress/coagulation | −5.02 | −5.40 | −5.46 | −5.93 | −2.01 |
| PLAUR: plasminogen activator, urokinase receptor | Receptor, coagulation cascade | −2.86 | −3.15 | −2.19 | −2.27 | 1.87 |
| GBP1: guanylate binding protein 1, interferon-inducible | GTPase activity | −8.65 | −9.73 | −6.93 | −7.03 | 2.11 |
| AKR1C3: aldo-keto reductase family 1, member C3 | Lipid metabolic process | 2.55 | 6.04 | −9.62 | ||
| FAM83A: family with sequence similarity 83, member a | Unknown | −7.04 | −5.52 | −2.45 | −2.85 | −3.33 |
| FAM46C: family with sequence similarity 46, member C | Unknown | 2.53 | 2.57 | 2.67 | 3.08 | −4.25 |