Table 1.
VeIP/VIP for initial salvage therapy of advanced GCT
| Reference | Regimen | Retrospective vs Prospective | No. Evaluable | CR (%) | Durable CR (%) |
|---|---|---|---|---|---|
| Pizzocarro et al21 | VIPa or VeIPa | R | 36 | 20 (56) | 15 (42) |
| Farhat et al28 | VIPb or VeIPb | R | 54 | 24 (44) | 10 (19)b |
| McCaffrey et al22 | VIP or VeIP | R | 56 | 20 (36) | 13 (23) |
| Loehrer et al23 | VeIP | P | 135 | 67 (50) | 32 (24) |
| Pico et al31 | VIP or VeIP | P | 122 | 51 (42) | 31 (25) |
Abbreviations: No., number; CR, complete response; VIP, etoposide, ifosfamide, and cisplatin; VeIP, vinblastine, ifosfamide, and cisplatin; R, retrospective; P, prospective; NS, not stated.
a
Modified dosing schedule as outlined in text
b
Seven of 24 patients with CR went on to receive consolidative high-dose chemotherapy with stem cell rescue.