Table 5.
Serum liver damage enzyme levels in relationship with related risk factors in the three groups.
| Risk factor | Unexposed (n = 145) | Low exposed (n = 183) | High exposed (n = 994) | p-Value | ||||
|---|---|---|---|---|---|---|---|---|
| HBV infected [n (%)] | 3 (2.1) | 4 (2.2) | 37 (3.7) | 0.39a | ||||
| Hepatotoxic medicines used [n (%)] | 7 (4.8) | 9 (4.9) | 65 (6.5) | 0.55a | ||||
| HBV-negative, no hepatotoxic medicine use [n (%)] | 135 (93.1) | 170 (92.9) | 892 (89.7) | 0.22a | ||||
| ALT (U/L)b | 14.0 (12.6–15.4) | 16.1 (14.5–17.7) | 14.8 (14.2–15.4) | 0.14c | ||||
| AST (U/L)b | 27.6 (26.2–29.0) | 30.3 (29.3–31.3) | 33.4 (32.8–34.0) | 0.01c | ||||
| GGT (U/L)b,c | 14.8 (13.7–15.8) | 17.0 (16.2–17.8) | 16.2 (15.7–16.7) | 0.18c | ||||
| ALP (U/L)b,c | 281.3 (269.5–293.1) | 285.6 (272.9–298.3) | 288.7 (281.4–296.0) | 0.00c | ||||
| Enzyme abnormalities [n (%)] | 6 (4.4) | 10 (5.9) | 96 (10.8) | 0.22a | ||||
| aChi-square test. bValues are 95% CI. cKruskal–Wallis test. | ||||||||