Table 2.

Biomarker distribution measured in umbilical cord blood and maternal blood from the total mother–newborn population.

Mothers					Newborns					p-Value (mothers vs. newborns)
Biomarker	n	Mean ± SD	Median (25th–75th percentile)	n	Mean ± SD	Median (25th–75th percentile)
Total population
MNBN/1,000 BN		223		2.85 ± 2.18		2.36 (1.40–3.85)		251		1.86 ± 1.59		1.53 (0.77–2.47)		< 0.001
MNMONO/1,000 MONO		223		0.72 ± 1.04		0.42 (0.00–1.01)		251		0.62 ± 0.71		0.44 (0.00–0.97)		0.770
CBPI		223		1.64 ± 0.25		1.70 (1.47–1.83)		251		1.56 ± 0.22		1.58 (1.44–1.71)		< 0.001
Folate (ng/mL)		42		851.40 ± 365.32		794.20 (525.25–1119.53)		33		766.65 ± 272.63		714.20 (580.35–917.95)		0.445
Vitamin B12 (pg/mL)		88		234.67 ± 115.97		204.70 (152.28–300.28)		79		275.50 ± 156.33		256.60 (163.80–321.30)		0.130
Paired population
MNBN/1,000 BN		180		2.95 ± 2.27		2.50 (1.48–3.88)		182		1.77 ± 1.41		1.55 (0.77–2.30)		< 0.001
MNMONO/1,000 MONO		180		0.73 ± 1.10		0.40 (0.00–1.00)		182		0.67 ± 0.74		0.50 (0.00–1.02)		0.313
CBPI		180		1.66 ± 0.24		1.72 (1.53–1.83)		182		1.59 ± 0.20		1.61 (1.48–1.74)		< 0.001
Folate (ng/mL)		30		880.50 ± 376.57		814.70 (525.50–1222.00)		30		770.53 ± 286.06		676.10 (577.80–929.63)		0.327
Vitamin B12 (pg/mL)		76		234.53 ± 117.79		203.05 (152.93–291.68)		76		275.62 ± 155.29		258.90 (164.63–319.70)		0.129
Differences between mothers and newborns were analyzed with a Mann–Whitney U-test.