Table 3.
Adjusteda associations [OR (95% CI)] between serum PFC exposure and ADHD or learning problemsb among children 12–15 years of age, C8 Health Project, Mid-Ohio Valley, 2005–2006 (n = 3,571).
| Serum PFC (ng/mL) | ADHD diagnosis | ADHD diagnosis + medication | Learning problemb | |||
|---|---|---|---|---|---|---|
| PFOA | ||||||
| Quartile 1: 0.6 to < 13.0 | 1.00 | 1.00 | 1.00 | |||
| Quartile 2: 13.0 to < 28.2 | 1.18 (0.91–1.53) | 1.39 (0.95–2.04) | 1.13 (0.86–1.47) | |||
| Quartile 3: 28.2 to < 65.3 | 0.93 (0.71–1.21) | 1.25 (0.85–1.83) | 0.93 (0.71–1.21) | |||
| Quartile 4: 65.3 to 2070.6 | 0.79 (0.60–1.04) | 0.87 (0.58–1.32) | 0.96 (0.73–1.26) | |||
| PFOS | ||||||
| Quartile 1: 0.25 to < 14.8 | 1.00 | 1.00 | 1.00 | |||
| Quartile 2:14.8 to < 20.2 | 0.91 (0.70–1.19) | 1.40 (0.94–2.08) | 0.78 (0.60–1.01) | |||
| Quartile 3: 20.2 to < 27.9 | 0.92 (0.71–1.21) | 1.38 (0.92–2.06) | 0.68 (0.52–0.89) | |||
| Quartile 4: 27.8 to 202.1 | 0.99 (0.76–1.30) | 1.32 (0.88–1.99) | 0.71 (0.54–0.93) | |||
| PFHxS | ||||||
| Quartile 1: 0.25 to < 2.9 | 1.00 | 1.00 | 1.00 | |||
| Quartile 2: 2.9 to < 5.2 | 1.46 (1.10–1.93) | 1.32 (0.87–1.99) | 1.31 (1.00–1.71) | |||
| Quartile 3: 5.2 to < 10.1 | 1.45 (1.10–1.91) | 1.32 (0.88–1.97) | 1.08 (0.82–1.43) | |||
| Quartile 4: 10.1 to 276.4 | 1.53 (1.15–2.04) | 1.42 (0.94–2.13) | 1.05 (0.79–1.40) | |||
| PFNA | ||||||
| Quartile 1: 0.25 to < 1.2 | 1.00 | 1.00 | 1.00 | |||
| Quartile 2: 1.2 to < 1.5 | 1.16 (0.89–1.51) | 1.12 (0.76–1.64) | 0.97 (0.74–1.25) | |||
| Quartile 3: 1.5 to < 2.0 | 0.96 (0.74–1.24) | 0.99 (0.67–1.45) | 0.86 (0.66–1.11) | |||
| Quartile 4: 2.0 to 24.1 | 1.00 (0.75–1.32) | 1.15 (0.78–1.71) | 0.73 (0.55–0.98) | |||
| aAdjusted for age (continuous) and sex. bLearning problem denotes a positive response to the question “Has a representative from a school or a health professional ever told you that you have/had a learning problem?” | ||||||