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. 2011 Aug 10;36(13):2616–2628. doi: 10.1038/npp.2011.145

Figure 3.

Figure 3

GRM2/3−/− mice show a dissociation between performance on appetitive and aversive spatial memory tasks. (a) GRM2/3−/− mice (n=25) learned the swimming SRM Y-maze task at the same rate as wild-type mice (wt; n=25). Data shown are mean percent correct responses (±SEM) for each block of 5 trials. Inset: in a probe test on day 7, GRM2/3−/− mice spent an equal or greater (p=0.051) proportion of their time searching in the arm that had previously held the platform, relative to wild-type mice. (b) GRM2/3−/− mice (n=25) displayed slower acquisition of the appetitive SRM Y-maze task than wild-type controls (n=25). Data shown are mean percent correct responses (±SEM) for each block of 10 trials. Order of testing and the rooms in which the tests were performed were fully counterbalanced. Chance performance is indicated by the dashed line. *p<0.05.