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. 2011 Aug 17;36(13):2659–2673. doi: 10.1038/npp.2011.156

Figure 5.

Figure 5

Higher effect size values for BOLD fMRI than VAS pain rating data. Effect size values greater than 0.5 were considered to be large effects, whereas values between 0.1 and 0.5 were small-to-moderate effects (Cohen, 1988). BOLD fMRI effect size values are higher than VAS pain rating effect sizes in each of the comparisons. Whereas the greatest effect for both BOLD fMRI and VAS data was consistently observed for the BUP cohort (BUP vs saline), the APREP cohort (APREP vs saline) demonstrated smallest effects. The blue line demonstrates that the VAS pain rating effect size specific to the BUP cohort was consistently lower than the BOLD fMRI effect sizes for the four ROIs.