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Open-field behavior of MAO-ANeo mice in comparison with WT and MAO-A KO counterparts. (a) Typical locomotor pathways of WT, MAO-ANeo, and MAO-A KO mice in the open field. (b–d) MAO-ANeo mice show significant reductions in (b) total distance, (c) time spent in the central zone, and (d) percent locomotor activity in the central zone. The values are represented as the mean±SEM. **P<0.01 and ***P<0.001 compared with WT mice, and #P<0.05 and ##P<0.01 compared with MAO-ANeo mice.
