Skip to main content
. 2010 Oct 1;10(7):703–711. doi: 10.4161/cbt.10.7.12904

Figure 4.

Figure 4

Effects of VEGF or VEGF + SU11248 on the proliferation of cultured mouse breast cancer (E0771) cells, human umbilical vein endothelial cells (HUVEC) and human aortic smooth muscle cells (HAS MC). VEGF (10 ng/ml) caused a 42% increase in the proliferation of E0771 cells, compared to the control (p < 0.01; n = 8) and there was a significant decrease in the proliferation of E0771 cells treated with VEGF plus SU11248 vs. the control (65%, p < 0.01) (A). VEGF caused a 2-fold increase in the proliferation of HUVEC vs. the control (p < 0.01; n = 8), but its action was completely abolished by SU11248 (B). Neither VEGF nor SU11248 exerted any effect on the proliferation of cultured HAS MC (1) that do not express VEGF receptors (C).