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Central administration of ghrelin increases BSX mRNA expression and FoxO1, pFoxO1, and pCREB protein expression in male and female rats. BSX mRNA levels in ARC (A, B) and pCREB, CREB, pFoxO1, FoxO1, CHOP-10, and peIF2α hypothalamic protein levels (C, D) of male and female rats after i.c.v. treatment with vehicle (open bars) or ghrelin (solid bars). *P < 0.05, **P < 0.01, ***P < 0.001 vs. vehicle. 3V, third ventricle.
