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Anti Xa activity in plasma versus time of fondaparinux in rats after oral administration of LNCs formulations (A) = CTAB-LNCs, (B) = SA-LNCs, different Fp doses (0.5, 2 or 5 mg/kg).
Notes: Data are shown as the mean concentration, and error bars represent the SEM (n = 3–5).
Abbreviations: IU, international unit; mL, milliliter; mg, milligram; kg, kilogram; CTAB, hexadecyltrimethyl ammonium bromide; LNC, lipid nanocapsule; SA, stearylamine; Fp, fondaparinux; SEM, standard error mean.
