Table 1. Muc2, Tff3 and luminal BA Levels in the Neonatal Rat NEC Model.
Group (n) | Muc2+cells1 | Muc2 mRNA | Tff3+cells1 | Total luminal BA2 |
DF (12) | 7.5±0.3 | 1.0±0.1 | 3.3±0.3 | 0.7±0.2 |
NEC (12) | 3.7±0.4* | 1.2±0.3 | 5.6±0.7* | 1.7±0.3# |
NEC+Chol (12) | 7.1±0.5 | 1.1±0.5 | 5.7±0.6* | 0.3±0.1 |
Mean positive cells/100 intestinal epithelial cells ± SD.
Mean µg/L BAs/mg ileum ± SD.
Mean steady-state mRNA for the dam-fed (DF) group was assigned a value of 1.0 and the mean mRNA levels for the NEC and NEC+cholestyramine (NEC+Chol) groups were determined relative to this number.
*P≤0.05;
P≤0.01.