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. 2011 Dec 5;6(12):e28458. doi: 10.1371/journal.pone.0028458

Figure 2. Interactions at the dimer-dimer interface involve residues at the C-terminal end of Co-CA.

Figure 2

A: Superposition of Co-CA monomer A in blue on Hi-CA monomer E in green (pdb code 2A8D [14]). Whereas the C-terminal helix in Hi-CA extends over 4 turns, the helix in Co-CA breaks after two turns at residue Arg-213. B: The final 24 residues at the C-terminal in Co-CA are directed over the tetramer interface and make extensive hydrophobic- and hydrogen-bond contacts with a symmetry-related monomer (pink). Residues involved in dimer-dimer contacts are shown as ball-and-sticks. Bonds from carbon atoms in monomer A are colored in yellow, and bonds from carbon atoms in the symmetry-related monomer C are colored in white.