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. 2011 Dec 5;6(12):e28458. doi: 10.1371/journal.pone.0028458

Figure 4. The active site of acetazolamide-inhibited Co-CA (Co-CA-AZM).

Figure 4

A: 2|F obs|-|F calc| map of the catalytic site contoured at 1σ level. For clarity the map is calculated only over the acetazolamide, the glycerol molecule, and the zinc ion. Residues are shown in ball-and stick, zinc ion in cyan, and water molecules as red spheres. The glycerol molecule is labeled GOL. Primed residue numbers indicate symmetry-related residues in the dimer. B: Detailed view over the active site and the hydrogen-bonding network in Co-CA-AZM.