Table 1.
Characteristic | Alzheimer's disease (n=48) | No dementia (n=1352) | P value | Participants (n=1409) | Non-participants (n=591) | P value (t test) |
---|---|---|---|---|---|---|
Male/female (%) | 40/60 | 38/62 | 0.73* | 38/62 | 36/64 | 0.57* |
Duration of follow up (years) | 20.6 (4.5) | 20.9 (4.9) | 0.75 | 20.9 (4.9) | ||
Age (years): | ||||||
Midlife | 54.0 (4.7) | 50.2 (6.0) | <0.001 | 50.4 (6.0) | 51.2 (5.9) | 0.007 |
Re-examination | 74.7 (3.8) | 71.1 (4.0) | <0.001 | 71.3 (4.0) | ||
Education (years) | 6.7 (2.7) | 8.5 (3.5) | <0.001 | 8.4 (3.5) | 7.4 (2.9) | <0.001 |
Mini-mental state examination | 20.4 (3.0) | 26.1 (2.0) | <0.001 | 25.9 (2.4) | ||
Body mass index (kg/m2): | ||||||
Midlife | 27.6 (4.0) | 26.5 (3.7) | 0.038 | 26.6 (3.7) | 27.2 (4.5) | 0.002 |
Re-examination | 27.8 (4.4) | 27.8 (4.3) | 0.994 | 27.8 (4.3) | ||
Systolic blood pressure (mm Hg): | ||||||
Midlife | 152.7 (18.2) | 143.9 (19.8) | 0.002 | 144.3 (19.9) | 150.2 (21.7) | <0.001 |
Re-examination | 150.4 (23.5) | 151.5 (23.4) | 0.747 | 151.4 (23.3) | ||
Diastolic blood pressure (mm Hg): | ||||||
Midlife | 91.2 (9.5) | 89.1 (10.9) | 0.182 | 89.2 (10.9) | 91.7 (11.3) | <0.001 |
Re-examination | 80.4 (11.5) | 80.5 (11.2) | 0.965 | 80.4 (11.2) | ||
Cholesterol (mmol/l): | ||||||
Midlife | 7.2 (1.0) | 6.7 (1.2) | 0.001 | 6.7 (1.2) | 7.0 (1.3) | <0.001 |
Re-examination | 6.0 (1.0) | 5.8 (1.0) | 0.234 | 5.8 (1.0) |
χ2 test was used.