Table 3.
Relation of medical history and vascular characteristics to Alzheimer's disease. Values are numbers (percentages) unless otherwise stated
| Characteristic* | Alzheimer's disease (n=48) | No dementia (n=1352) | P value† |
|---|---|---|---|
| Myocardial infarction: | |||
| Midlife | 3 (6) | 34 (2.5) | 0.245 |
| Re-examination | 18 (38) | 189 (14.0) | <0.001 |
| Cerebrovascular symptoms: | |||
| Midlife | 0 (0) | 19 (1.4) | 1.00 |
| Re-examination | 9 (19) | 89 (6.6) | 0.004 |
| Diabetes mellitus: | |||
| Midlife | 0 (0) | 16 (1.2) | 0.929 |
| Re-examination | 6 (13) | 88 (6.5) | 0.177 |
| Antihypertensive drug treatment: | |||
| Midlife | 13 (27) | 194 (14.3) | 0.015 |
| Re-examination | 19 (40) | 488 (36.1) | 0.621 |
| Cholesterol lowering drug treatment: | |||
| Re-examination | 10 (21) | 208 (15.4) | 0.436 |
| Smoking: | |||
| Midlife | 23 (48) | 577 (42.7) | 0.474 |
| Re-examination | 19 (40) | 498 (36.8) | 0.929 |
| Alcohol use: | |||
| Midlife | 29 (60) | 956 (70.7) | 0.633 |
| Re-examination | 22 (46) | 964 (71.3) | 0.003 |
*
Information was obtained from detailed questionnaires about medical history and medical conditions and events diagnosed by a physician. Midlife and re-examination indicates the visit when the questionnaire was answered.
†
χ2 test was used.