Table 2. Multinomial logistic regression analysis showing the association of the KCNJ11 E23K variant with progression to prediabetes and progression to T2DM at the end of the 12-year study.
Genotype count | ||||||||
n | KK | EK | EE | HWE P-value | EAF | OR (95%CI) | unadjusted P | |
Progression to T2DM | 198 | 23 | 86 | 89 | 0.749 | 0.333 | 1.01 (0.81–1.26) | 0.961 |
Progression to prediabetes | 209 | 35 | 96 | 78 | 0.556 | 0.397 | 1.32 (1.07–1.63) | 0.011 |
No progression | 1185 | 137 | 513 | 535 | 0.407 | 0.332 | 1.00 (Ref) | - |
HWE: Hardy-Weinberg Equilibrium; EAF: Effect allele frequency; n: Number; OR: Odds ratio; CI: Confidence interval; P: P-value.