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. Author manuscript; available in PMC: 2012 Oct 11.
Published in final edited form as: J Am Coll Cardiol. 2011 Oct 11;58(16):1715–1727. doi: 10.1016/j.jacc.2011.07.017

Figure 1. Impact of injection of IK17-Fab on atherosclerosis in LDLR−/− mice in Study 1.

Figure 1

(A) Plasma IK17-Fab concentrations and (B) IK17-Fab mouse IgG or IgM immune complexes in Study 1. Increases in both IgM and IgG titers are significant (P< 0.001 ANOVA with Bonferroni correction). (C) Representative aortic images from a PBS Control or IK17-Fab injected LDLR−/− mouse stained with Sudan IV. (D) Quantitative analysis of en face atherosclerotic area in the entire aorta. Data are expressed as percentage of Sudan IV stained area of entire aorta examined.

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