Table 1.
Proteins quantified with more than 1.5 fold changes, with IPI numbers, protein names, average ratios and S.D. listed. (Other information including peptides number, sequence coverage and p-value was listed in Table S1.)
| IPI Number | Protein Name | Ratio (treated/untreated) |
|---|---|---|
| A. Histones and hnRNPs | ||
| IPI00455457 | Histone H3 | 1.57 ± 0.08 |
| IPI00807545 | Herogeneous nuclear ribonucleoprotein K | 1.61 ± 0.09 |
| B. translation related factors | ||
| IPI00014263 | Eukaryotic translation initiation factor 4H | 0.63 ± 0.14 |
| IPI00925413 | EIF4G1 protein | 0.67 ± 0.13 |
| IPI00290460 | eIF3 p42 | 0.69 ± 0.06 |
| C. Enzymes | ||
| IPI00218414 | Carbonate dehydratase II | 0.17 ± 0.01 |
| IPI00877726 | Acidic-type mitochondrial creatine kinase | 0.19 ± 0.05 |
| IPI00010130 | Glutamine synthetase | 0.38 ± 0.13 |
| IPI00006957 | Dehydrogenase/reductase SDR family member 7 | 0.42 ± 0.02 |
| IPI00021167 | Interferon-inducible double stranded RNA-dependent protein kinase activator A | 0.53 ± 0.03 |
| IPI00328170 | Mannosyl-oligosaccharide glucosidase | 0.56 ± 0.01 |
| IPI00221108 | Thymidylate synthase | 0.58 ± 0.09 |
| IPI00008475 | 3-hydroxy-3-methylglutaryl coenzyme A synthase | 0.58 ± 0.39 |
| IPI00065671 | Cytidine monophosphokinase 2 | 0.63 ± 0.01 |
| IPI00020944 | Farnesyl-diphosphate farnesyltransferase | 0.64 ± 0.01 |
| IPI00006937 | Non-canonical ubiquitin-conjugating enzyme 1 | 0.67 ± 0.11 |
| IPI00027851 | CDNA FLJ53927, highly similar to β-hexosaminidase α chain (EC 3.2.1.52) | 0.63 ± 0.07 |
| IPI00399307 | Prolylcarboxypeptidase (Angiotensinase C), isoform CRA_b | 1.53 ± 0.06 |
| IPI00306325 | Protein tyrosine phosphatase, receptor type, C | 1.52 ± 0.04 |
| IPI00797038 | CDNA FLJ50710, highly similar to Phosphoenolpyruvate carboxykinase (GTP), mitochondrial (EC 4.1.1.32) | 1.53 ± 0.03 |
| IPI00293564 | 3-hydroxy-3-methylglutarate-CoA lyase | 1.54 ± 0.05 |
| IPI00329185 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase γ-2 | 1.54 ± 0.04 |
| IPI00221224 | Alanyl aminopeptidase | 1.56 ± 0.71 |
| IPI00290684 | 2'(3')-polynucleotidase | 1.58 ± 0.03 |
| IPI00012426 | Retinoid-inducible serine carboxypeptidase | 1.71 ± 0.75 |
| IPI00023728 | Conjugase | 1.77 ± 0.71 |
| IPI00020632 | Argininosuccinate synthase | 2.19 ± 0.24 |
| IPI00236556 | 84 kDa myeloperoxidase | 4.03 ± 0.35 |
| D. Others | ||
| IPI00418471 | Vimentin | 0.25 ± 0.09 |
| IPI00010341 | Bone marrow proteoglycan | 0.26 ± 0.04 |
| IPI00645608 | Interferon regulatory factor 2-binding protein 1 | 0.49 ± 0.06 |
| IPI00027933 | Low molecular mass protein 10 | 0.50 ± 0.05 |
| IPI00000686 | Probable RNA-binding protein 19 | 0.51 ± 0.09 |
| IPI00018236 | Cerebroside sulfate activator protein | 0.52 ± 0.01 |
| IPI00023087 | Cell proliferation-inducing gene 50 protein | 0.52 ± 0.07 |
| IPI00419595 | Endoglycan | 0.53 ± 0.06 |
| IPI00006377 | Proteasome maturation protein | 0.55 ± 0.07 |
| IPI00005670 | Cell division cycle protein 123 homolog | 0.55 ± 0.09 |
| IPI00002135 | ERIC-1 | 0.56 ± 0.12 |
| IPI00306749 | Human lung cancer oncogene 3 protein | 0.56 ± 0.05 |
| IPI00784161 | Tat-cotransactivator 2 protein | 0.56 ± 0.06 |
| IPI00924510 | Putative uncharacterized protein RIF1 | 0.56 ± 0.12 |
| IPI00795267 | Gametocyte-specific factor 1 | 0.56 ± 0.08 |
| IPI00303753 | Hcp β-lactamase-like protein C1orf163 | 0.56 ± 0.12 |
| IPI00856042 | Leucine-rich repeat-containing protein 58 | 0.57 ± 0.03 |
| IPI00296259 | Endoplasmic reticulum stress-response protein 25 | 0.58 ± 0.07 |
| IPI00031647 | Programmed cell death protein 2-like | 0.59 ± 0.09 |
| IPI00012788 | A34.5 | 0.59 ± 0.11 |
| IPI00031801 | Cold shock domain-containing protein A | 0.59 ± 0.11 |
| IPI00306043 | CLL-associated antigen KW-14 | 0.60 ± 0.09 |
| IPI00002214 | Importin subunit α-2 | 0.60 ± 0.06 |
| IPI00043565 | Coiled-coil domain-containing protein 16 | 0.61 ± 0.08 |
| IPI00143753 | 140 kDa Ser/Arg-rich domain protein | 0.61 ± 0.08 |
| IPI00297169 | Lymphocyte cytosolic protein 2 | 0.61 ± 0.06 |
| IPI00384180 | Dopamine receptor-interacting protein 3 | 0.61 ± 0.04 |
| IPI00298935 | JmjC domain-containing histone demethylation protein 2B | 0.61 ± 0.10 |
| IPI00006442 | Coilin | 0.61 ± 0.20 |
| IPI00798034 | Protein KRI1 homolog | 0.61 ± 0.09 |
| IPI00022386 | ATP-binding protein associated with cell differentiation | 0.62 ± 0.05 |
| IPI00007004 | Ribosomal RNA-processing protein 15 | 0.62 ± 0.11 |
| IPI00171127 | Ubiquitin-associated protein 2 | 0.62 ± 0.14 |
| IPI00003318 | Protein FON | 0.62 ± 0.05 |
| IPI00291930 | Clathrin interactor 1 | 0.62 ± 0.05 |
| IPI00008490 | Protein unc-93 homolog B1 | 0.62 ± 0.02 |
| IPI00006176 | Hepatocyte growth factor-regulated tyrosine kinase substrate | 0.62 ± 0.10 |
| IPI00103064 | Exocyst complex component 7 | 0.62 ± 0.06 |
| IPI00100247 | Thioredoxin domain-containing protein 13 | 0.63 ± 0.01 |
| IPI00465288 | Finger protein in nuclear bodies | 0.63 ± 0.11 |
| IPI00024167 | ABT1-associated protein | 0.63 ± 0.08 |
| IPI00221035 | RNA polymerase B transcription factor 3 | 0.63 ± 0.03 |
| IPI00027180 | CAAX prenyl protease 1 homolog | 0.63 ± 0.05 |
| IPI00007729 | Nucleolar protein 7 | 0.64 ± 0.05 |
| IPI00647185 | Centrosomal protein 170kDa | 0.64 ± 0.09 |
| IPI00020961 | Apoptosis regulator Bcl-2 | 0.64 ± 0.05 |
| IPI00009005 | Activating enhancer-binding protein 4 | 0.64 ± 0.04 |
| IPI00218829 | G1 to S phase transition protein 1 homolog | 0.64 ± 0.01 |
| IPI00004233 | Antigen KI-67 | 0.64 ± 0.05 |
| IPI00015808 | Autoantigen NGP-1 | 0.65 ± 0.12 |
| IPI00018192 | NOP seven-associated protein 1 | 0.65 ± 0.03 |
| IPI00028481 | Oncogene c-mel | 0.65 ± 0.05 |
| IPI00470779 | α-taxilin | 0.65 ± 0.1 |
| IPI00384541 | Regulation of nuclear pre-mRNA domain-containing protein 2 | 0.65 ± 0.06 |
| IPI00217686 | Protein ftsJ homolog 3 | 0.65 ± 0.15 |
| IPI00215768 | γ-glutamylcysteine synthetase | 0.65 ± 0.07 |
| IPI00514856 | Protein NICE-4 | 0.65 ± 0.2 |
| IPI00185919 | La ribonucleoprotein domain family member 1 | 0.65 ± 0.16 |
| IPI00005717 | Estrogen-related receptor α | 0.66 ± 0.06 |
| IPI00889000 | Neurochondrin | 0.66 ± 0.10 |
| IPI00432363 | Microtubule-actin cross-linking factor 1, isoform 4 | 0.66 ± 0.14 |
| IPI00412415 | ATP-dependent chromatin-remodeling protein | 0.67 ± 0.04 |
| IPI00291064 | AN1-type zinc finger protein 1 | 0.67 ± 0.12 |
| IPI00219168 | β-V spectrin | 0.67 ± 0.05 |
| IPI00012773 | Metastasis-associated protein MTA1 | 0.67 ± 0.17 |
| IPI00001960 | Chloride intracellular channel protein 4 | 1.50 ± 0.35 |
| IPI00024971 | Oxysterol-binding protein 1 | 1.51 ± 0.11 |
| IPI00033153 | mRNA export factor TAP | 1.51 ± 0.08 |
| IPI00015148 | GTP-binding protein smg p21B | 1.52 ± 0.03 |
| IPI00878557 | δ transcription factor | 1.54 ± 0.05 |
| IPI00219219 | 14 kDa laminin-binding protein | 1.54 ± 0.36 |
| IPI00394994 | Nesprin-3 | 1.55 ± 0.02 |
| IPI00103483 | Cofactor of BRCA1 | 1.56 ± 0.07 |
| IPI00017289 | Nucleic acid-binding protein RY-1 | 1.57 ± 0.73 |
| IPI00020075 | Abhydrolase domain-containing protein 10, mitochondrial | 1.57 ± 0.08 |
| IPI00009368 | Sideroflexin-1 | 1.57 ± 0.11 |
| IPI00793723 | CDK7/cyclin-H assembly factor | 1.61 ± 0.10 |
| IPI00848090 | cDNA, FLJ94534, highly similar to Homo sapiens capping protein (actin filament), gelsolin-like(CAPG), mRNA | 1.64 ± 0.04 |
| IPI00903062 | cDNA FLJ43948 fis, clone TESTI4014924, highly similar to cytoplasmic FMR1 interacting protein 1 (CYFIP1), transcript variant 1, mRNA | 1.66 ± 0.13 |
| IPI00478758 | UPF0557 protein C10orf119 | 1.69 ± 0.07 |
| IPI00007812 | Endomembrane proton pump 58 kDa subunit | 1.70± 0.27 |
| IPI00922511 | cDNA FLJ54854, highly similar to junctional adhesion molecule A | 1.71 ± 0.30 |
| IPI00478231 | Rho cDNA clone 12 | 1.94 ± 0.24 |
| IPI00410067 | Zinc finger antiviral protein | 1.99 ± 0.30 |
| IPI00295940 | cDNA FLJ55508, highly similar to Sad1/unc-84-like protein 2 | 1.99 ± 0.74 |
| IPI00007061 | Golgi transport 1 homolog B | 2.18 ± 0.30 |
| IPI00397229 | CD97 antigen | 2.25 ± 0.27 |
| IPI00071826 | cDNA FLJ55391 | 2.53 ± 0.10 |
| IPI00021812 | Desmoyokin | 2.55 ± 0.30 |
| IPI00418169 | Annexin A2 | 2.56 ± 0.96 |
| IPI00032313 | Calvasculin | 2.67 ± 0.28 |
| IPI00847793 | Dermcidin isoform 2 | 2.69 ± 0.08 |
| IPI00375156 | Putative neutrophil cytosol factor 1B | 3.31 ± 0.75 |
| IPI00386208 | Drug-sensitive protein 1 | 9.56 ± 6.28 |