. Author manuscript; available in PMC: 2012 Dec 5.

Published in final edited form as: Mol Pharm. 2011 Oct 7;8(6):2021–2031. doi: 10.1021/mp200329f

Table 1.

Partial list of histone deacetylase inhibitors currently in clinical trials for the treatment of cancer.

Class	Compound
Aliphatic acids	Valproic acid
Aliphatic acids	AR-42 (OSU-HDAC42)
Hydroxamic Acids	*Vorinostat (suberoylanilide hydroxamic acid, SAHA)
	Belinostat (PXD101)
	Dacinosat (LAQ824)
	Panobinostat (LBH589)
	Resminostat (4SC-201)
	PCI-24781
	SB939
	CHR2845
	CHR3996
	JNJ-26481585
Benzamides	Entinostat (MS-275)
	Mocetinostat (MGCD0103)
	4SC-202
Cyclic peptides	*Romidepsin (depsipeptide, FK228, FR901228)

Compounds marked with an * are currently FDA approved. Belinostat is currently in registration trials.