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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Biol Psychiatry. 2011 Oct 5;71(1):75–83. doi: 10.1016/j.biopsych.2011.08.014

Fig. 1.

Fig. 1

Regulation of stress-enabled hippocampal LTD. (A) Reliable LFS-induced, stress-enabled LTD was found in WT slices, but not p75NTR-/- slices (P<2×10-6). (B) LTD induced by NMDA (7min, 10μM) was similar between WT and p75NTR-/- mice (P>0.05). (C) LTD induced by carbachol (10min, 50μM) was similar between WT and p75NTR-/-(P>0.05). (D) Reliable stress-enabled LTD was induced in slices from scrambled peptide-injected, but not GluA23Y peptide(P<5×10-5). (E) Reliable stress-enabled LTD was induced in slices from saline injected mice, but not scopolamine injected mice (P<0.003). (F) NMDA-induced LTD was normal in slices from scopolamine injected mice. Note saline group is shared with control group in Fig. 1B.