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Body weight. Total body weight (mean ± SEM) of adult mice from the three genetic lines Ras-GRF1, GENA53, and Ras-GRF1 OE. Ras-GRF1 WT (n = 24); Ras-GRF1 KO (n = 24); GENA53 WT (n = 24); GENA53 (n = 24); Ras-GRF1 OE WT (n = 24); Ras-GRF1 OE MUT (n = 24). Each mutant is compared with its respective wild-type by means of an independent-samples t-test. P-value symbols: black star = p < 0.001; black triangle = p < 0.01; asterisk = p < 0.05.
