Figure 2.
Vasodilation responses to endothelial- and smooth muscle-dependent dilating agents in ischemic and non-ischemic profunda femoris arteries, in vivo. (A) Vasodilation responses to increasing doses of acetylcholine (Ach), applied in 10−x M increments, and a maximal dose of sodium nitroprusside (SNP) in day-14 ischemic (gray) and non-ischemic (black) arteries. (B) Vasodilation responses to maximal doses of Ach (10−4 M) and SNP (10−4 M) in day-14 ischemic (gray) and contralateral control (black) profunda femoris arteries. Data points are on a relative scale, with resting diameter represented by 0%. *p ≤ 0.05 versus day-14 ischemic.