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. 2011 Nov 11;52(12):8791–8798. doi: 10.1167/iovs.11-8203

Figure 2.

Figure 2.

Effect of reversal of hyperglycemia on mitochondrial biogenesis. Gene expression of (a) PGC1 and (c) NRF1 were quantified in rat retina by real-time RT-PCR using custom primers (TaqMan; Applied Biosystems). The values were normalized to β-actin in each sample. Protein expression of (b) PGC1 and (d) NRF1 were quantified in the retina by Western blot analysis. The accompanying histograms show the expression of PGC1 and of NRF1, adjusted to the expression of β-actin. Values are represented as mean ± SD obtained from five to seven animals in each group.