Figure 6.
Extent of tissue responses to polypropylene microspheres with –OH, -COOH and control –CH2 functionality were assessed based on (A) capsule thickness and (B) cell infiltration distance into particle implants. Polypropylene (PP) microspheres coated with high, medium and low densities of –OH and –COOH groups along with control –CH2 were subcutaneously implanted in Balb/C mice. The animals were sacrificed at 2 weeks post implantation. Values shown reflect the average thickness of the capsule ± SD (n= 3 for -OH, -COOH and –CH2).