Table 1.
Allele frequencies of the CTG repeat in controls and schizophrenic patients, including subtypes, course specifiers and positive family history, and results of Fisher's exact test and Monte Carlo method
| Fisher's test | Monte Carlo | ||||||
| Subjects (n) | Alleles (%) | 6R vs 9-13R | method | ||||
| 6R | 9R | 10R | 11R | 13R | P value | P value | |
| Controls (100) | 38 (19.0) | 72 (36.0) | 78 (39.0) | 12 (6.0) | 0 (0.0) | 0.7095 | 0.9547 |
| Schizophrenic patients (102) | 42 (20.6) | 67 (32.8) | 80 (39.2) | 14 (6.9) | 1 (0.5) | 0.7095 | 0.9547 |
| Subtypes | |||||||
| Paranoid (22) | 10 (22.7) | 13 (29.5) | 17 (38.6) | 4 (9.1) | 0 (0.0) | 0.5378 | 0.7538 |
| Disorganized (38) | 21 (27.6) | 27 (35.5) | 23 (30.3) | 4 (5.3) | 1 (1.3) | 0.1392 | 0.3808 |
| Residual (29) | 8 (13.8) | 18 (31.0) | 28 (48.3) | 4 (6.9) | 0 (0.0) | 0.4386 | 0.6666 |
| Others (13) | 3 (11.5) | 9 (34.6) | 12 (46.1) | 2 (7.7) | 0 (0.0) | 0.4304 | 0.7869 |
| Course | |||||||
| Episodic (64) | 24 (1 8.8) | 48 (37.5) | 45 (35.2) | 10 (7.8) | 1 (0.8) | 1.0000 | 0.9207 |
| Continuous (31) | 15 (24.2) | 15 (24.2) | 28 (45.2) | 4 (6.5) | 0 (0.0) | 0.3709 | 0.4709 |
| Others (7) | 3 (21.4) | 4 (28.6) | 7 (50.0) | 0 (0.0) | 0 (0.0) | 0.7346 | 0.8137 |
| Prominent negative symptoms (42) | 17 (20.2) | 26 (31.0) | 34 (40.5) | 6 (7.1) | 1 (1.2) | 0.8696 | 0.8388 |
| Positive family history (46) | 19 (20.7) | 31 (33.7) | 34 (37.0) | 7 (7.6) | 1 (1.1) | 0.7522 | 0.9002 |
6R, 9R, 10R, 11R and 13R indicate 6, 9, 10, 11 and 13 repeats of CTG, respectively.