Table 1.

Aβ₄₀ aggregation in relation to control (100%), log D (pH 7.4) values of alkaloids [30] and their association constants with Aβ₄₀ peptide [16].

Compound	Aggregation [%]of control	Log D pH 7.4 [30]	Log Ka 108 [M−1] [16]
Lobeline	59.1 ± 18.9	2.14	0.90
Arecoline	66.1 ± 13.1	0.71	2.30
Pseudopelletierine	130.9 ± 11.2	−0.96	0.57
Trigonelline	97.0 ± 20.4	−3.31	0.28
Pyridoxine	97.5 ± 11.4	−1.45	-