Table 3.
Comparison of microalbuminuria and stage 3 to 5 CKD rates between African Americans with no or one risk allele, two APOL1 risk alleles, and European Americans
| European American No Risk Alleles | African American |
P |
|||
|---|---|---|---|---|---|
| No or One Risk Alleles | Two Risk Alleles | AA (no or one) versus EA | AA (two) versus EA | ||
| Microalbuminuria (%) | |||||
| total | 3.45 | 9.17 | 17.54 | 0.00033 | 1.72 × 10−8 |
| nondiabetic (n = 1559) | 2.31 | 5.95 | 16.50 | 0.00073 | 1.3 × 10−9 |
| diabetic (n = 266) | 17.57 | 27.35 | 25.00 | 0.167 | 0.592 |
| GFR4 < 60 ml/min per 1.73 m2 (%) | |||||
| total | 2.04 | 2.47 | 5.51 | 0.26 | 0.042 |
| nondiabetic (n = 1559) | 1.57 | 1.68 | 5.77 | 0.48 | 0.0039 |
| diabetic (n = 266) | 8.11 | 6.99 | 3.57 | 0.28 | 0.30 |
| GFR6 < 60 ml/min per 1.73 m2 (%) | |||||
| total | 1.95 | 2.60 | 6.36 | 0.36 | 0.0080 |
| nondiabetic (n = 1559) | 1.47 | 1.68 | 6.73 | 0.53 | 0.00039 |
| diabetic (n = 266) | 8.11 | 7.86 | 3.57 | 0.39 | 0.30 |