Table II.

Inactivation of Dehydrogenase Activity by the Indicated Organic Nitrate Following a 10-min Incubation

	WT hALDH2	WT hALDH1a1
Control	100 ± 9	100 ± 13
0.1 mM NTG	NAD*	22 ± 11*
1 mM ISDN	4.6 ± 7.9*	0.44 ± 1.0*
1 mM IS-5-MN	102 ± 14	89 ± 4**

Data are expressed as% of vehicle control ± SD, n = 3–4

NAD no activity detected

*p < 0.001 vs. WT, **p < 0.01