Table 3.
Albendazole acts synergistically with radiation in MM and SCLC cells.
| % Survival | ||||
|---|---|---|---|---|
| Cell line | ABZ (nM) | CI Values | SER | Plating Eff. |
| A375 | 100 | 0.981 | ||
| 500 | 0.701 | 1.45 | 43% | |
| A2058 | 100 | 0.921 | ||
| 500 | 0.675 | 1.32 | 29% | |
| H1530 | 100 | 0.89 | ||
| 500 | 0.528 | 1.28 | 34% | |
| H446 | 100 | 0.906 | ||
| 500 | 0.485 | 1.20 | 26% | |
Combination Index values for ABZ and radiation. Values less than 0.9 indicate a synergistic relationship, values between 0.9 and 1.0 indicate an additive relationship, and values greater than 1.0 indicate an antagonistic relationship.