TABLE 3.

Number of mouse pups derived from zygotes/oocytes retrieved following IVF

Treatment	Starting oocytes/zygotes	2- to 4-cell embryos formed and transferred [n (%)]	Pups born [n (%)]
−rAC	80	32 (40)	5 (6.25)
+rAC	89	78 (87.6)	30 (33.7)
P value		<0.003	<0.02

Superovulated female mice were fertilized in vivo, and the zygotes (or unfertilized oocytes) were cultured in the presence or absence of rAC for 24–48 h. The number of 2- to 4-cell embryos formed was recorded. For both groups, the 2- to 4-cell embryos were then implanted into hosts, and the number of pups born was recorded. Percentages (in parentheses) are relative to the starting number of zygotes/oocytes. P values compare treatment with and without rAC.