Table 2.
Adjusted β estimates from linear regression analyzing the association between Hp genotype and square root transformed CAC volume, stratified by the presence of CAC at baseline
Adjusting for age and sex only | Including covariates from backwards selection model* | ||||
---|---|---|---|---|---|
Characteristic | β estimate | p-value | β estimate | p-value | |
Hp genotype * diabetes interaction*presence of CAC at baseline interaction | N/A | 0.001 | N/A | 0.001 | |
CAC not present at the baseline visit | Hp 2-2 vs. 2-1/1-1 in patients with diabetes | 0.82 | 0.03 | 0.74 | 0.05 |
Hp 2-2 vs. 2-1/1-1 in controls without diabetes | 0.67 | 0.2 | 0.83 | 0.11 | |
CAC present at the baseline visit | Hp 2-2 vs. 2-1/1-1 in patients with diabetes | -0.34 | 0.3 | -0.31 | 0.33 |
Hp 2-2 vs. 2-1/1-1 in controls without diabetes | -2.02 | 0.52 | 0.24 | 0.7 | |
Age | 0.11 | < 0.0001 | 0.1 | < 0.0001 | |
Female vs. male | -1.17 | < 0.0001 | 0.22 | 0.001 | |
Systolic blood pressure | N/A | 0.01 | < 0.0001 | ||
HDL cholesterol | N/A | 0.01 | 0.003 |
* Adjusting for age, sex, systolic blood pressure and HDL-cholesterol