Table 3.
Oxidative stress, serum cytokines, serum nitrites and nitrates during albumin and gelatin infusions
| Parameter | Before treatment | Albumin infusion period | Wah-Out period | Gelatin infusion period | Statistical analyses |
|---|---|---|---|---|---|
| Plasma total anti-oxydant power (copper reducing equivalent microM) | 0.23 ± 0.08 | 0.26 ± 0.11 | 0.27 ± 0.13 | 0.22 ± 0.11 | p > 0.05 at the repeated measures ANOVA |
| Hydrogen peroxyde μg/ml | 29.97 ± 7.3 | 10.87 ± 1.9 | 14.57 ± 2.5 | 11.19 ± 2.4 | p < 0.001 at the repeated measures ANOVA |
| Lipid peroxides (H202 equivalent) μM/1 | 50 [13.84-189.5] | 7 [7-209.4] | 37.30 [7-305] | 38.20 [7.82-298.7] | p < 0.005 at the Friedman test |
| Lactoferrin at the beginning of the dialysis session (ng/ml) | 245.7 ± 154 | 199.3 ± 133 | 154 ± 36.98 | 153.7 ± 29.79 | p > 0.05 at the repeated measures ANOVA |
| Lactoferrin at the end of the dialysis session (ng/ml) | 159.7 ± 40.52 | 144.5 ± 48 | 152.8 ± 31.42 | 154.9 ± 74.31 | p > 0.05 at the repeated measures ANOVA |
| IL6 at the beginning of the dialysis session (pg/ml) | 5.55 ± 8.19 | 2.44 ± 2.82 | 2.19 ± 2.87 | 1.74 ± 2.51 | p > 0.05 at the repeated measures ANOVA |
| IL6 at the end of the dialysis session (pg/ml) | 6.88 ± 7.56 | 6 ± 3.98 | 4.26 ± 2.19 | 5 ± 3.4 | p > 0.05 at the repeated measures ANOVA |
| IL8 at the beginning of the dialysis session (pg/ml) | 32.77 ± 43.79 | 21 ± 9.89 | 24 ± 18 | 19.83 ± 13.89 | p > 0.05 at the Friedman test |
| TNF α at the beginning of the dialysis session pg/ml | 9.85 ± 10.82 | 9.13 ± 5.87 | 8.04 ± 10.22 | 4.72 ± 3.59 | p > 0.05 at the repeated measures ANOVA |
| TNF α at the end of the dialysis session pg/ml | 8.33 ± 7.17 | 7.59 ± 4.67 | 5.40 ± 2.82 | 4.51 ± 2.96 | p > 0.05 at the repeated measures ANOVA |
| Serum nitrates + nitrites at the beginning of the dialysis session (μmol/1) | 49 ± 24.90 | 50.35 ± 30.87 | 53.66 ± 26 | 55.35 ± 28.42 | p > 0.05 at the repeated measures ANOVA |
| Serum nitrates + nitrites at the end of the dialysis session (μmol/I) | 45.34 ± 27.16 | 48.58 ± 17.78 | 47.27 ± 20 | 53.70 ± 34.48 | p > 0.05 at the repeated measures ANOVA |
The values are given either as mean ± SD in case of gaussian distribution or as medium [range] in case of non parametric distribution