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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Mol Cancer Res. 2010 Nov 29;9(1):25–35. doi: 10.1158/1541-7786.MCR-10-0497

Table 1.

Protein concentrations in conditioned media from monocultures and cocultures

Proteins 344SQ LF CAF LF/344SQ CAF/344SQ
MCP-1 9.11 282.46 2,524.16 1,182.22a 2,711.63a
MIP-1α 21.29 21.67 59.85 33.2 177.97a
MIP-1β 0.75 2.71 60.64 14.16a 142.34a
RANTES 0.5 1.22 19.65 9.40a 29.24
Eotaxin 76.12 36.8 149.24 86.01 196.3
KC 486.38 52.69 1,191.99 809.42 2,370.50a
MIP-2 2.24 3.9 118.74 31.07a 1,119.31a
MIG 2.51 1.58 31.82 10.08a 69.44a
bFGF 1.94 2.07 12.57 5.28a 19.08a
PDGF-β 38.86 22.36 17.41 13.67 13.58
VEGF-A 61.94 8.3 409.68 85.75a 712.91a
VEGF-D 0.92 6.33 3.82 0.5 11.75
IL-1α 0.2 0.33 1.71 0.43 1.56
IL-1β 6.87 3.36 23.35 10.15a 34.51a
IL-2 0.75 0.7 1.55 0.69 1.64
IL-3 0.03 0.18 0.24 0.09 0.29
IL-4 0.04 1.67 0.21 0.04 0.27
IL-5 0.41 0.6 1.28 0.49 1.66
IL-6 1.29 30.2 1,838.95 128.90a 675
IL-9 5.15 2.35 23.67 4.42 24.96
IL-10 0.87 0.48 2.08 0.85 2.95a
IL-12(p40) 0.43 0.32 1.65 0.54a 2.21a
IL-12(p70) 22.89 22.64 39.19 28.82a 41.69a
IL-13 34.08 27.36 53.69 30.29 61.19
IL-17 0.23 0.34 0.97 0.25 1.22
IL-15 2.38 1.78 40.17 12.2a 76.29a
IL-18 16.02 18.35 55.4 19.44 78.42*
TGF-β1 852.39 110.68 1,875.37 903.56a 2,687.85a
G-CSF 10.09 3.67 47.43 32.76a 122.32a
GM-CSF 16.37 3.93 12.22 16.21 27.56a
M-CSF 13.29 32.54 106.95 59.80a 132.21a
IFN-γ 3.24 2 8.58 3.48 10.85
TNF-α 7.67 5.82 15.7 8.61 20.92a
LIF 30.62 7.74 103.94 36.23 171.74a

NOTE: Protein concentrations are pg/mL. Comparisons (coculture vs. either of 2 monocultures) were based on Dunnett’s test.

a

Protein concentrations that were significantly different (P < 0.05) in coculture relative to that of either of the monocultures.