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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Future Med Chem. 2011 Nov;3(15):1909–1934. doi: 10.4155/fmc.11.136

Figure 1. Microsomal prostaglandin E synthase-1 and structural homologies with other proteins.

Figure 1

(A) View from the top of the trimeric complex. The structure was downloaded from the PDB database (3DWW). GSH is shown in ball and sticks. (B) Structural similarities between mPGES-1 (3DWW, in orange), and MGST-1 (2H8A.A, in cyan), FLAP (2Q7M.F, in cyan), Huntingtin interacting protein 12 or HIP-12 (1R0D.A, in cyan) and the protein tyrosine kinase 2 β or PTK2 (3GM3.A, in cyan).