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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Future Med Chem. 2011 Nov;3(15):1909–1934. doi: 10.4155/fmc.11.136

Table 1.

Sequences and structure similarities with microsomal prostaglandin E synthase-1 (PDB: 3DWW).

Rank Chain Title p-value RMSD Len1§ Len2 ID# (%) COV1†† (%) COV2‡‡ (%)
1 2H8A.A Microsomal glutathione S-transferase 1 3.41E-13 1.70 142 121 17 82 97
2 2Q7M.F Arachidonate 5-lipoxygenase-activating protein 2.35E-8 3.13 142 149 5 89 85
3 1R0D.A Huntingtin-interacting protein 12 1.17E-7 3.21 142 194 5 84 61
4 2BL2.J V-type sodium ATP synthase subunit K 1.35E-7 3.49 142 158 8 82 74
5 2OKU.B Acyl-CoA dehydrogenase family protein 2.85E-7 3.21 142 116 5 75 92
6 3GM3.A Protein tyrosine kinase 2β 3.06E-7 3.10 142 133 2 64 68
7 1XG2.B Pectinesterase inhibitor 7.32E-7 3.23 142 151 5 63 59
8 1X91.A Invertase/pectin methylesterase inhibitor family protein 7.78E-7 3.29 142 149 5 63 60
9 2QYW.A Vesicle transport through interaction with t-SNAREs 1B homolog 1.02E-6 2.69 142 96 6 46 69
10 1NFN.A Apolipoprotein E3 1.05E-6 2.99 142 132 5 62 67
2827 1Z9H.A Membrane-associated prostaglandin E synthase-2 polypeptide (L) 0.0257 8.45 142 247 -1 82 42
16724 1EJF.B Human co-chaperone P23 (cPGES) 0.946 3.65 142 110 -1 26 34

Title for protein chain description.

RMSD value of the alignment.

§

The length of the chain 1.

The length of the chain 2.

#

The percentage sequence identity in the alignment.

††

The coverage, or percentage, of aligned residues in chain 1.

‡‡

The coverage, or percentage, of aligned residues in chain 2.