Table 3.

Endogenous lipids, fatty acids and prostaglandin endoperoxide analogs.

Number	Compound	Structure	IC50[μM]†	Ref.
1	LTC4		5	[26]
2	15-deoxy-Δ12,14-PGJ2		0.3	[73]
3	U-51605 (PGH2 stable analog)		<10 >100	[73] [26]
4	U-44069 (PGH2 stable analog)		NI	[26]
5	U-46619 (PGH2 stable analog)		NI	[26]
6	Arachidonic acid		0.3	[73]
7	Docosahexaenoic acid		0.3	[73]
8	Eicosapentaenoic acid		0.3	[73]
9	Palmitic acid		2	[73]

^†Determined by cell-free mPGES-1 activity assays.

NI: No significant inhibition; PGH₂: Prostaglandin endoperoxide.