TABLE 3. Timing of Death by Transfusion Group.
HSD (N = 220) | HS (N = 256) | NS (N = 376) | P* | HSD-NS† (95% CI) | HS-NS† (95% CI) | |
---|---|---|---|---|---|---|
0 units PRBC in first 24 h, n (%) | 91 (41.6) | 104 (40.8) | 139 (37.1) | 0.48 | 4.5 (−4.0 to 13.0) | 3.7 (−4.4 to 11.8) |
Died in field, n (%) | 4 (1.8) | 5 (2.0) | 3 (0.8) | −‡ | 1.0‡ | 1.2‡ |
Died in field or ED, n (%) | 14 (6.4) | 23 (9.0) | 13 (3.5) | 0.01 | 2.9 (−1.2 to 7.0) | 5.6 (1.2 to 9.9) |
Died within 6 h of admission, n (%) | 15 (6.8) | 23 (9.0) | 14 (3.7) | 0.02 | 3.1 (−1.1 to 7.3) | 5.3 (1.0 to 9.6) |
Died within 28 d, n (%) | 22 (10.0) | 31 (12.2) | 18 (4.8) | <0.01 | 5.2 (0.4 to 10.1) | 7.4 (2.5 to 12.2) |
1 to 9 units PRBC in first 24 h, n (%) | 92 (42.0) | 111 (43.5) | 175 (46.7) | 0.51 | −4.7 (−13.3 to 4.0) | −3.1 (−11.4 to 5.1) |
Died in field, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | −‡ | 1.0‡ | 1.2‡ |
Died in field or ED, n (%) | 11 (5.0) | 10 (3.9) | 14 (3.7) | 0.73 | 1.3 (−2.5 to 5.1) | 0.2 (−3.2 to 3.6) |
Died within 6 h of admission, n (%) | 12 (5.5) | 17 (6.7) | 25 (6.7) | 0.83 | −1.2 (−5.5 to 3.1) | 0.0 (−4.3 to 4.3) |
Died within 28 d, n (%) | 19 (8.7) | 24 (9.4) | 46 (12.3) | 0.31 | −3.6 (−8.9 to 1.8) | −2.9 (−8.1 to 2.4) |
>10 units PRBC in first 24 h, n (%) | 36 (16.4) | 40 (15.7) | 61 (16.3) | 0.97 | 0.2 (−6.4 to 6.7) | −0.6 (−6.7 to 5.6) |
Died in field, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | −‡ | 1.0‡ | 1.2‡ |
Died in field or ED, n (%) | 0 (0.0) | 0 (0.0) | 3 (0.8) | −‡ | −0.8‡ | −0.8‡ |
Died within 6 h of admission, n (%) | 9 (4.1) | 9 (3.5) | 22 (5.9) | 0.35 | −1.8‡ | −2.3‡ |
Died within 28 d, n (%) | 15 (6.8) | 14 (5.5) | 32 (8.5) | 0.34 | −1.7 (−6.4 to 3.1) | −3.0 (−7.3 to 1.3) |
For differences in means/proportions across all 3 treatment arms.
Difference in mean/proportion with 95% CI for that difference.
Cells to small for valid interval estimation using normal approximation and for chi-square P value deaths in the field, field or ED, and within 6 hours are cumulative; percentages are computed on the basis of total number treated on each arm.